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Q

quantumdynamics

Too old for this h*ck
Oct 28, 2018
28
Hi guys,

I'v bought some chloroquine tablets online and I need a method to test them for purity.

I got no background in chemistry whatsoever. Any tips/advice'll be appreciated.

Q
 
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Trashcan

Trashcan

Trash
Aug 31, 2018
1,234
Boost. I hope your question gets answered.
 
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V

Voldmort

Experienced
Sep 23, 2018
287
you can try to rely on the results of a thin layer chromatography. is risky because you will not work with the results of a chromatographic plate with a sample of pure chloroquine.
in this technique you could do several tests with different solvents until you have finished, but obviously it would be very expensive.
for the technique you would need small smooth plates of glass or metal; some grams of Fluorescent Silica; organic solvents / and water; paper; dropper.

the interpretation of the results would be that there were several marks after the elucidations, the sample is severely contaminated; if it has only one mark, it is theoretically pure, but difficultly you will find only
a brand, even because most of the chemicals have 2-3% impurity. technique will not show the numerical amount of purity without the use of some sophisticated apparatus in the laboratory so it is a risk.

I think you will give up establishing purity because it is very difficult to achieve.
if there were a reaction with 100% yield that gave off a gas, it would be much easier to establish the purity up quantitatively if you use a balance.
 
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Q

quantumdynamics

Too old for this h*ck
Oct 28, 2018
28
@Voldmort Ok, well, is there anyway to know if what I have is enough to ctb? In other words, if what I have is the actual medicine and not an unreliable knock-off/a result of a scam?
 
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V

Voldmort

Experienced
Sep 23, 2018
287
@Voldmort Ok, well, is there anyway to know if what I have is enough to ctb? In other words, if what I have is the actual medicine and not an unreliable knock-off/a result of a scam?

I thought you already knew that it was chloroquine, that way the technique would be the chromatography ... I got it wrong.
I did not get to that part in organic chemistry, so I'm useless, I'm sorry! maybe nitrous acid will identify the amine groups of chloroquine from a reaction, but I'm not really sure.
 
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