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Zhoutongwei

Member
May 12, 2025
19
Let's take the use of antacids as an example:

If antacids are used → the production of nitric oxide is reduced → the drop in blood pressure caused by vasodilation occurs more slowly → this means it will take longer for us to lose consciousness → we are more likely to vomit while still conscious (and thus able to drink a second dose), rather than vomiting after losing consciousness (in which case we wouldn't know how much was vomited, nor would we be able to take a second dose of SN).

From this perspective, antacids are indeed very useful. Their purpose is not only to reduce the waste caused by SN reacting with stomach acid, but I believe their greatest significance is to delay the time we lose consciousness, thus ensuring that we are still awake when vomiting.

This debate is similar to whether the dosage of benzodiazepines should be, as stated in PPH, "enough to knock you out quickly" — I think rapidly entering a comatose state is unwise for a simple reason: if we vomit while unconscious, how can we drink a second dose?

What is your opinion?You're welcome to discuss.
 
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2messdup

2messdup

Enlightened
Feb 10, 2024
1,292
Let's take the use of antacids as an example:

If antacids are used → the production of nitric oxide is reduced → the drop in blood pressure caused by vasodilation occurs more slowly → this means it will take longer for us to lose consciousness → we are more likely to vomit while still conscious (and thus able to drink a second dose), rather than vomiting after losing consciousness (in which case we wouldn't know how much was vomited, nor would we be able to take a second dose of SN).

From this perspective, antacids are indeed very useful. Their purpose is not only to reduce the waste caused by SN reacting with stomach acid, but I believe their greatest significance is to delay the time we lose consciousness, thus ensuring that we are still awake when vomiting.

This debate is similar to whether the dosage of benzodiazepines should be, as stated in PPH, "enough to knock you out quickly" — I think rapidly entering a comatose state is unwise for a simple reason: if we vomit while unconscious, how can we drink a second dose?

What is your opinion?You're welcome to discuss.
As I understand it, 25g is more than enough to kill you. People have died after much less. The second drink is belt and braces but as long as you don't vomit all of the initial amount immediately you still have a good chance of dying with some vomiting of the first drink. Personally I'm avoiding antacids as I want as little as possible in my stomach but using benzos to reduce anxiety. Not going to aim for benzos to knock me out tho as I'm going to do the two drinks just to be sure.
 
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Zhoutongwei

Member
May 12, 2025
19
As I understand it, 25g is more than enough to kill you. People have died after much less. The second drink is belt and braces but as long as you don't vomit all of the initial amount immediately you still have a good chance of dying with some vomiting of the first drink. Personally I'm avoiding antacids as I want as little as possible in my stomach but using benzos to reduce anxiety. Not going to aim for benzos to knock me out tho as I'm going to do the two drinks just to be sure.
Regarding benzodiazepines, we share the same stance — we take them to reduce anxiety, absolutely not to hasten unconsciousness.

Once we fall unconscious, we can no longer know whether we will vomit afterward, let alone take a second dose.
Although many sources claim that even if vomiting occurs after the first dose, the amount of SN already absorbed by the body is sufficient to be lethal, I still believe there is a risk — because you don't truly know how much has been absorbed, or whether it's enough to cause death.
I don't want to gamble on probability. That's why I want to stay conscious for as long as possible, to be able to deal with vomiting if it happens.
 
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EmptyBottle

EmptyBottle

Aera23 ^u^
Apr 10, 2025
167
I doubt that vomiting will be enough to both clear all the SN from the stomach, and clear enough of the absorbed SN from the bloodstream to make the hyper-lethal dose non-lethal. It may ofc slow the death down... but asphyxiating on stomach contents while unconscious may actually speed up the death
 
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Zhoutongwei

Member
May 12, 2025
19
I've recently developed a new perspective on the use of antacids: by reducing stomach acid and raising the pH level, antacids can slow down the breakdown and gastric emptying of the antiemetic drug taken 10 minutes earlier. This delays the onset of the drug's maximum effect, which is not helpful for achieving our goal of preventing vomiting.
Since it's difficult for us to determine the exact amount needed, I now believe that antacids should not be used.
 
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derrick876

Member
May 20, 2025
5
Regarding benzodiazepines, we share the same stance — we take them to reduce anxiety, absolutely not to hasten unconsciousness.

Once we fall unconscious, we can no longer know whether we will vomit afterward, let alone take a second dose.
Although many sources claim that even if vomiting occurs after the first dose, the amount of SN already absorbed by the body is sufficient to be lethal, I still believe there is a risk — because you don't truly know how much has been absorbed, or whether it's enough to cause death.
I don't want to gamble on probability. That's why I want to stay conscious for as long as possible, to be able to deal with vomiting if it happens.
What quantity and kind of benzos and are you planning on taking?
 
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TheVanishingPoint

Member
May 20, 2025
9
Your reasoning is extremely clear. I agree that remaining conscious long enough to assess potential vomiting is crucial when using sodium nitrite.
The widespread belief that quickly losing consciousness is safer overlooks the real risk of partial regurgitation without awareness and the impossibility of taking a second dose.
In this sense, antacids serve a dual purpose: they reduce chemical waste and help preserve strategic timing.
The only risk is psychological. Staying awake too long may induce panic. But if the person is prepared and composed, your logic is solid.
 
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Valhala

Valhala

Arcanist
Jul 30, 2024
486
No one has survived 25 g of SN unless (most often due to SI) they changed their mind and sought help or if they found him in the critical few hours after SN ingestion. Delaying unconsciousness is actually frustrating because it increases SI and prolongs the agony. It is true that the protocol recommends having another cup ready (some protocols even a third cup) for safety's sake, but I repeat: there is no documented case of surviving 25 g of SN regardless of the intensity and amount of vomiting. Lethal is considered already 1.5 / 2 g. of SN, so that the necessary amount will be resorbed through the small intestine even if he vomits while unconscious, considering that unconsciousness occurs in a minimum of 5 minutes, often after 15/20 or more minutes, which is quite enough time for the critical dose of SN to be resorbed.
 
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