Opiates

[Richard Langford]

I've been doing a lot of research into Opiates in terms of CTB - to combine them with a Benzo and possibly alcohol to potentiate them. I started out looking at...

1) Oramorph. It's available on the DW but would involve drinking significant amounts (and an AE as with all as Nausea comrs into it). Notwithstanding that, its possible to be sucessful.

2) Oxycontin/Oxycodone. These are again available and are more powerful than Morphine. Nausea comes into it and its difficult to get a MG figure that would prove conclussive. Anyone?

3) Heroin. Readily available but needs to be tested as per potency. Can be administered IV (but I have difficult veins), rectally or IM. IM is easy but does anyone know the bioavailability re that method and how it effects the time frame and indeed any issues re such?

4) Nitazenes again available but masquerading as something else in pill form. Potentially very strong. Anyone aware of any issues in taking large amounts orally (obviously Nausea)? These 'may' present a simplier option.

Please chip in if you have any knowledge re suchlike.

 

[Richard Langford]

Bounce.

 

[thatisitguy]

I attempted to CTB via fentanyl overdose back in September. The media makes opiates look so deadly that if you pop one hydrocondone then you will die. I purchased 30 "blues" and swallowed all of them with Nyquil back in September. Didn't die or need medical treatment. I tested the pills and they did contain fentanyl. I was outraged that it didn't kill me. All of a sudden the fentanyl doomsayers came up with all these reasons as to why I didn't die. Despite my failure, I ended up getting 100 or so more "blues" and hopefully my next attempt will be successful. I really don't want to try a gun with my luck. My point is that potency is key with opiates.

 

[supergold#2]

heyyo, just an fyi, fentanyl has a really low oral bioavailability (probably even moreso if they're blues, bc those things are compressed so fucking tightly you could probs use em to break a windshied. tried crushing one on my phone screen the first time, totalled my phone and literally ripped a hole in my dollar bill. i even started using a hammer for a bit lmao)

your best bet for blues is to vaporize em off a foil, but they are INCREDIBLY poorly dispersed (i.e. vaporizing one half of a pill migh barely get you high, while a literal crumb from the same pill on the other side might be enough to overdose. i seen many a seasoned junkie fall victim to it, on the hotspot where i used to live, it was almost an every-other-day occurence it seems like

also, another thing to take into account is the possibility they might not be fent, but nitazenes instead (common in my [old] area, more specifically etidonozene). honestly the way benzofuranes have been being developed, it's really hard to get a guage on bioavailabilities, usually its pretty safe to assume vaporization will be consistently high though.

(i also have never met ANYONE that's tried shooting them, so idk if it'd actually even work, i do know they're extremely poorly water soluble though)

I've been doing a lot of research into Opiates in terms of CTB - to combine them with a Benzo and possibly alcohol to potentiate them. I started out looking at...

1) Oramorph. It's available on the DW but would involve drinking significant amounts (and an AE as with all as Nausea comrs into it). Notwithstanding that, its possible to be sucessful.

2) Oxycontin/Oxycodone. These are again available and are more powerful than Morphine. Nausea comes into it and its difficult to get a MG figure that would prove conclussive. Anyone?

3) Heroin. Readily available but needs to be tested as per potency. Can be administered IV (but I have difficult veins), rectally or IM. IM is easy but does anyone know the bioavailability re that method and how it effects the time frame and indeed any issues re such?

4) Nitazenes again available but masquerading as something else in pill form. Potentially very strong. Anyone aware of any issues in taking large amounts orally (obviously Nausea)? These 'may' present a simplier option.

Please chip in if you have any knowledge re suchlike.

idk much about the first one, but if your only ROA is oral, i'd say it's not gonna work. even if you managed to black out without puking, you'll just throw it up in your sleep. "best" possible scenario is you choke on your vomit, which leads to you potentially waking up at least partially (due to adrenaline), and that's a fucking awful way to go.

oxy is more 50/50, depending on the preparation. if it's roxicodone brand, it is in fact possible to vaporize them, but all other brands (that i'm aware of) take in depth pharmicokinetic knowledge (far past me, at least) in order to not just cinder and denature. if you do a cold water extraction, you'd be able to remove the oxy from the acetaminophen, and then make a liquid solution from it which you could plug (wouldn't recomend shooting, pills have high probability of causing clots quickly, which might prevent the drug from actually reaching your (liver i think?)), or if you're willing to risk potential sepsis, IM injection would be possible, but if you don't succeed, shit might suck.

as for the heroin (my truest love; it's all blues and fetty round here), i am QUEEN of the intramuscular injection, it's always been my favorite ROA for heroin, just can't do it often, bc necrosis risk lol. but to answer you, it's almost identical in bioavailability to IV (assuming you get it into muscle, not fat or skin), like 98% im to 99% iv, the come up time is about like 3 or 4 times as long as iv i wanna say? it's honestly still really quick, you just don't really get that overwhelming rush that you do from iv, it feels a lot more like the smoking high, maybe a lil more intense tho.

finally, nitazenes (if you google "benzofuranes" you can find most types on wikipedia, though bluelight has tons of firsthand if you're willing to dig)
there is SUCH a broad variety (increasing all the time) to these that there's no one rule to tell you absolutely how strong they'll be, HOWEVER if you exclude most of the iso- and like 75% of the proto- family of nitazenes, they're usually anywhere from 100x-10,000x the potentcy of fentanyl per gram, however, the manufacturers do (usually) put in the absolute bare minimum effort to make them *feel* as strong as whatever it's being sold as. if you can get your hands on etidonozene in bulk, itll be lights ouf from the second it even touches your mucas membranes/blood. there's a story of the inventor, a guy from slc, who upon synthesis started using, and by the time he was caught and forced to quit, they put him on like 10 times the max dose of [subs?/methadone? which ever one has agonist/partial antagonist combo], his withdrawals were still so insanely intense he ctb by his own hand (if that says anything about its potency?).
also, yeah they'll definitely make you nauseous, but usually you don't even notice because it's lights out the second you come up, unless you have a micrometer calibrated scale somehow? (also this is assuming they're pure)
it's also possible (and pretty quick) to develop a slight synthetic opioid tolerance which basically curbs the nausea (note: idk why, but in my experience fent and benzofurane nausea act similarly enogugh, a weirdly if you switch from fent to tar/oxy/hydro/etc or benzofuranes to tar/oxy/hydro/etc the nausea is like the first time all over again

 

[Richard Langford]

.

heyyo, just an fyi, fentanyl has a really low oral bioavailability (probably even moreso if they're blues, bc those things are compressed so fucking tightly you could probs use em to break a windshied. tried crushing one on my phone screen the first time, totalled my phone and literally ripped a hole in my dollar bill. i even started using a hammer for a bit lmao)

your best bet for blues is to vaporize em off a foil, but they are INCREDIBLY poorly dispersed (i.e. vaporizing one half of a pill migh barely get you high, while a literal crumb from the same pill on the other side might be enough to overdose. i seen many a seasoned junkie fall victim to it, on the hotspot where i used to live, it was almost an every-other-day occurence it seems like

also, another thing to take into account is the possibility they might not be fent, but nitazenes instead (common in my [old] area, more specifically etidonozene). honestly the way benzofuranes have been being developed, it's really hard to get a guage on bioavailabilities, usually its pretty safe to assume vaporization will be consistently high though.

(i also have never met ANYONE that's tried shooting them, so idk if it'd actually even work, i do know they're extremely poorly water soluble though)

idk much about the first one, but if your only ROA is oral, i'd say it's not gonna work. even if you managed to black out without puking, you'll just throw it up in your sleep. "best" possible scenario is you choke on your vomit, which leads to you potentially waking up at least partially (due to adrenaline), and that's a fucking awful way to go.

oxy is more 50/50, depending on the preparation. if it's roxicodone brand, it is in fact possible to vaporize them, but all other brands (that i'm aware of) take in depth pharmicokinetic knowledge (far past me, at least) in order to not just cinder and denature. if you do a cold water extraction, you'd be able to remove the oxy from the acetaminophen, and then make a liquid solution from it which you could plug (wouldn't recomend shooting, pills have high probability of causing clots quickly, which might prevent the drug from actually reaching your (liver i think?)), or if you're willing to risk potential sepsis, IM injection would be possible, but if you don't succeed, shit might suck.

as for the heroin (my truest love; it's all blues and fetty round here), i am QUEEN of the intramuscular injection, it's always been my favorite ROA for heroin, just can't do it often, bc necrosis risk lol. but to answer you, it's almost identical in bioavailability to IV (assuming you get it into muscle, not fat or skin), like 98% im to 99% iv, the come up time is about like 3 or 4 times as long as iv i wanna say? it's honestly still really quick, you just don't really get that overwhelming rush that you do from iv, it feels a lot more like the smoking high, maybe a lil more intense tho.

finally, nitazenes (if you google "benzofuranes" you can find most types on wikipedia, though bluelight has tons of firsthand if you're willing to dig)
there is SUCH a broad variety (increasing all the time) to these that there's no one rule to tell you absolutely how strong they'll be, HOWEVER if you exclude most of the iso- and like 75% of the proto- family of nitazenes, they're usually anywhere from 100x-10,000x the potentcy of fentanyl per gram, however, the manufacturers do (usually) put in the absolute bare minimum effort to make them *feel* as strong as whatever it's being sold as. if you can get your hands on etidonozene in bulk, itll be lights ouf from the second it even touches your mucas membranes/blood. there's a story of the inventor, a guy from slc, who upon synthesis started using, and by the time he was caught and forced to quit, they put him on like 10 times the max dose of [subs?/methadone? which ever one has agonist/partial antagonist combo], his withdrawals were still so insanely intense he ctb by his own hand (if that says anything about its potency?).
also, yeah they'll definitely make you nauseous, but usually you don't even notice because it's lights out the second you come up, unless you have a micrometer calibrated scale somehow? (also this is assuming they're pure)
it's also possible (and pretty quick) to develop a slight synthetic opioid tolerance which basically curbs the nausea (note: idk why, but in my experience fent and benzofurane nausea act similarly enogugh, a weirdly if you switch from fent to tar/oxy/hydro/etc or benzofuranes to tar/oxy/hydro/etc the nausea is like the first time all over again

Thanks for the comprehensive reply.

I was discussing (1) it with a pal on here. We thought with bioavailability, it'd have to be 2 or 3 300ml bottles which would be getting on for a Litre of liquids. That's a lot of liquids to have in your stomach - and Opiod Nausea also comes into it. You do hear about it but I'm guessing pre-existing health conditions come into it and a cumulative effect over time (not a one time thing).

In terms of (2) the Oxys what's wrong with just crushing and swallowing them? Bioavailability is supposed to be 80%+ so it wouldn't need many for the Opiate naive person you think (maybe a grams worth?)

Thank you for the Heroin (3) info. IM injections for me are very easy.

These (4) are apparently Isotonitazene masquerading as Oxycontin. These have been linked to a lot of deaths in the UK - just from recreational use. I'd again be looking to take these orally - which wouldn't be a problem? Would these (in theory) do a job? People are suggesting 1/2 or even a quarter of a pill in more than enough recreationally.

 

[supergold#2]

.

Thanks for the comprehensive reply.

I was discussing (1) it with a pal on here. We thought with bioavailability, it'd have to be 2 or 3 300ml bottles which would be getting on for a Litre of liquids. That's a lot of liquids to have in your stomach - and Opiod Nausea also comes into it. You do hear about it but I'm guessing pre-existing health conditions come into it and a cumulative effect over time (not a one time thing).

In terms of (2) the Oxys what's wrong with just crushing and swallowing them? Bioavailability is supposed to be 80%+ so it wouldn't need many for the Opiate naive person you think (maybe a grams worth?)

Thank you for the Heroin (3) info. IM injections for me are very easy.

These (4) are apparently Isotonitazene masquerading as Oxycontin. These have been linked to a lot of deaths in the UK - just from recreational use. I'd again be looking to take these orally - which wouldn't be a problem? Would these (in theory) do a job? People are suggesting 1/2 or even a quarter of a pill in more than enough recreationally.

so while you are correct that an increased volume would increase the rate of absorption, the increase is non-linear
(i think the word i'm looking for is a "logarithmic scale"? i.e it increases very gradually up to a point in which it spikes rapidly (but doing so would require having surface volume begin to catch up to or be greater than total volume of contents, it is genuinely not humanly possible to achieve)
the reason that i argue to substitute your ROA, isn't necessarily for increased bioavailability, but rather because (even with an anti-emetic, or 100) at doses required for lethality, the opioid nausea is not only triggered by muscinic receptors (i.e. hystamines, etc.; the transporter 99% of anti-emitics work on), but also seratogenic, dopaminic, anf neuroepinephrin receptors, essentially triggering your body to realize "hey, there's something in me that's fucking shit up, time to puke, and puke, and once there's nothing left, puke some more!"
therefore if all of the drug is in your stomach, an overwhelming majority is never going to even get the chance to be absorbed, no matter what type of cyp450 matabolic wombo combo you've got genetically encoded in your gut.
if there's an option to either put it in your butt (or biochemical extractio devised to make it IV or IM possible), just so once that purge response is inevitably triggered, your body won't be able to get it out.

as for the oxys (actual oxy) the same rules apply (except with the added possibility of vaporization if its exclusively the roxicodone brand)

ahhh okay, i know exactly what you're talking about, in my area we call them "blues", though I've also heard the term "dirty-30" thrown around lol.
so there's a couple things that you should keep in mind with these (assuming they're similar to the ones out here, which, honestly, very likely are if you're in the usa, canada, or central america):

• first (least importantly), be warned that these things will OBLITERATE anything glass if you try to crush them on it (also, will tear through dollar bills, plastic baggies, any paint, soft woods, etc. i've always had the best luck putting them on something sturdy, and just going buckwild with a hammer/back of a screwdriver/etc (make sure to like, tripple baggie them first, pieces will go everywhere otherwise).
• second, i have no idea what else goes in these things, but they seem to be both water and lipid inspluble, even when applied to heat, vigorous agitation, or strong household acids or base reactions (pure ascetic acid, calcium carbonate); meaning that they're essentially impossible to shoot (both iv and im), with extremely diminished results (i have yet to personally test, so this is secondhand info) in oral roa as well. earlier today i read a thread where someone took 30 orally and had no result (but, once again, i am entirely unsure how truthful this is considering this is the internet), however based my own research, this seems plausible. insufflation works, but it seems to be noticably weaker (than vaporization), by my best guesses, at least <1/2. i would assume since they are both mucus membranes, rectal ROA could potentially work (and if so, would be considerably higher bioavailability than snorting). ALL OF THAT BEING SAID: everyone i've ever met that uses blues vaporized it (if you know how to roll it along foil without burning it already no need to read my cheats ahead lol)
• the easiest way i've found (as a beginner, that is, because rolling is definitely no easy feat) is to first, crush all of your product, as finely as you humanly can, then take a rectangle of tinfoil (idk maybe like 8×4ish?) and fold it in half until it becomes a square. make sure you've folded it as tightly as you can, if the layerd are too far apart, it wont heat up enough. then, make a small, wide groove in the foil (like, 1/2 finger depth maybe, 2 fingers wide, 1 finger long?), this will be your pocket to ensure nothing falls out. as evenly and thinly as you can, spread your product over and around the groove. then, with your straw in your mouth (it's especially helpful if it has a trumpet shape on the far end), keeping the foil side of the straw no closer than 1" away from the foil, use a lighter to heat the foil from underneath. play with distances, you'll definitely notice when it starts vaporizing (and it also has the thickest, most vile chemical smell you've probably ever smelled; it will stick to a room for at least a day lol).
• to get the most out of a HIGH: start from the extremeties of the foil, even if there's no product there, and slowly move around and inward (inhaling the vapor as you go)
• to get the most product in your system before passing out CTB METHOD: use your lighter to heat up as much of the product as possible without it vaporizing (i.e like 2-3x distance as vaporizing, the goal isn't to get the foil warm (itll lose heat immediately) but to kinda prebake your product so it requires less effort to go). once youve done your best there, start dead center, but make sure you don't overinhale and fill your lungs with toomuch air, every millisecond counts here. move your lighter in an outward spiral, following the direction with your straw. chances are that you won't make it all the way through your product (but if you've put enough on, it won't matter) (hell, if you hit a hotspot (something blues are notorious for) you might not even need 1/10th of a pill)
• be warned, it's 0-60 in like 2 seconds flat, and if you're not familiar with the sensation, it can be pretty overwhelming (but still kinda enjoyable)
• side note: blues don't hit anything like heroin, dilauded, oxy, or any other naturally derived opioid; the long heavy, almost psychadelic, experience is completely absent, but rather in it's place it has a rush that's like, 10x it's strength (at bioequivalent doses), so be prepared for the freight train, or i guess the bus in this case.
• lastly, blues (and a majority of benzofuranes, as well as fentanyl too) have a very very short half life, whereas tar for example will give you a good 3-5 hours of fucked-up-ness (depending on tolerance), a first time user of blues and/or fentanyl with no tolerances can see the effects lasting just about an hour.
• it's highly recomended to take a polydrug combo to increase lethality, namely [opioid+benzo/barbituate] or [opioid+benzo/barbituate+opioid potentiator] (ive listed a few of below with my preferences), but please note that you should be prepared to stagger your drugs according to their individual onset of effect/peak blood plasma content times, as every one will be different depending on drug AND ROA:
  • benzos (xanax, valium, ativan, temazepam, oxazepam, flubromazepam (of the benzos, this one is prefered), etc.)
  • barbituate
    • methylphenobarbidal (prefered, over any benzo or barbituate) is commonly sold as "xanax" by the same people selling blues
    • phenobarbidal (i think this site calls it "N"?)
    • quaaludes (if you somehow find them, defs worth just to try, but pretty sure they're gone forever lol)
  • amyltryptaline (potentiator)
  • dextromethorphan, nighttime only (potentiator)
  • benedryl (nod-enhancer, helps with nausea)
  • (some sources (bluelight forums users) say clonidine can potentiate opioid effects, though i have not researched this)

last, and most importantly, you NEED to make sure that nobody will find you for bare minimum of an hour, preferably 2 or more, after you do whatever you decide.
MANY PEOPLE CARRY NARCAN, and can reverse an opioid overdose.
similarly, EVERY ambulance and hospital has drugs that can reverse benzo toxicity.
even if your heart and respiration had fully stopped, theres a chance you can be rescuscitated if you're found to soon (learned this the hard way lol)

 

[Richard Langford]

so while you are correct that an increased volume would increase the rate of absorption, the increase is non-linear
(i think the word i'm looking for is a "logarithmic scale"? i.e it increases very gradually up to a point in which it spikes rapidly (but doing so would require having surface volume begin to catch up to or be greater than total volume of contents, it is genuinely not humanly possible to achieve)
the reason that i argue to substitute your ROA, isn't necessarily for increased bioavailability, but rather because (even with an anti-emetic, or 100) at doses required for lethality, the opioid nausea is not only triggered by muscinic receptors (i.e. hystamines, etc.; the transporter 99% of anti-emitics work on), but also seratogenic, dopaminic, anf neuroepinephrin receptors, essentially triggering your body to realize "hey, there's something in me that's fucking shit up, time to puke, and puke, and once there's nothing left, puke some more!"
therefore if all of the drug is in your stomach, an overwhelming majority is never going to even get the chance to be absorbed, no matter what type of cyp450 matabolic wombo combo you've got genetically encoded in your gut.
if there's an option to either put it in your butt (or biochemical extractio devised to make it IV or IM possible), just so once that purge response is inevitably triggered, your body won't be able to get it out.

as for the oxys (actual oxy) the same rules apply (except with the added possibility of vaporization if its exclusively the roxicodone brand)

ahhh okay, i know exactly what you're talking about, in my area we call them "blues", though I've also heard the term "dirty-30" thrown around lol.
so there's a couple things that you should keep in mind with these (assuming they're similar to the ones out here, which, honestly, very likely are if you're in the usa, canada, or central america):

• first (least importantly), be warned that these things will OBLITERATE anything glass if you try to crush them on it (also, will tear through dollar bills, plastic baggies, any paint, soft woods, etc. i've always had the best luck putting them on something sturdy, and just going buckwild with a hammer/back of a screwdriver/etc (make sure to like, tripple baggie them first, pieces will go everywhere otherwise).
• second, i have no idea what else goes in these things, but they seem to be both water and lipid inspluble, even when applied to heat, vigorous agitation, or strong household acids or base reactions (pure ascetic acid, calcium carbonate); meaning that they're essentially impossible to shoot (both iv and im), with extremely diminished results (i have yet to personally test, so this is secondhand info) in oral roa as well. earlier today i read a thread where someone took 30 orally and had no result (but, once again, i am entirely unsure how truthful this is considering this is the internet), however based my own research, this seems plausible. insufflation works, but it seems to be noticably weaker (than vaporization), by my best guesses, at least <1/2. i would assume since they are both mucus membranes, rectal ROA could potentially work (and if so, would be considerably higher bioavailability than snorting). ALL OF THAT BEING SAID: everyone i've ever met that uses blues vaporized it (if you know how to roll it along foil without burning it already no need to read my cheats ahead lol)
• the easiest way i've found (as a beginner, that is, because rolling is definitely no easy feat) is to first, crush all of your product, as finely as you humanly can, then take a rectangle of tinfoil (idk maybe like 8×4ish?) and fold it in half until it becomes a square. make sure you've folded it as tightly as you can, if the layerd are too far apart, it wont heat up enough. then, make a small, wide groove in the foil (like, 1/2 finger depth maybe, 2 fingers wide, 1 finger long?), this will be your pocket to ensure nothing falls out. as evenly and thinly as you can, spread your product over and around the groove. then, with your straw in your mouth (it's especially helpful if it has a trumpet shape on the far end), keeping the foil side of the straw no closer than 1" away from the foil, use a lighter to heat the foil from underneath. play with distances, you'll definitely notice when it starts vaporizing (and it also has the thickest, most vile chemical smell you've probably ever smelled; it will stick to a room for at least a day lol).
• to get the most out of a HIGH: start from the extremeties of the foil, even if there's no product there, and slowly move around and inward (inhaling the vapor as you go)
• to get the most product in your system before passing out CTB METHOD: use your lighter to heat up as much of the product as possible without it vaporizing (i.e like 2-3x distance as vaporizing, the goal isn't to get the foil warm (itll lose heat immediately) but to kinda prebake your product so it requires less effort to go). once youve done your best there, start dead center, but make sure you don't overinhale and fill your lungs with toomuch air, every millisecond counts here. move your lighter in an outward spiral, following the direction with your straw. chances are that you won't make it all the way through your product (but if you've put enough on, it won't matter) (hell, if you hit a hotspot (something blues are notorious for) you might not even need 1/10th of a pill)
• be warned, it's 0-60 in like 2 seconds flat, and if you're not familiar with the sensation, it can be pretty overwhelming (but still kinda enjoyable)
• side note: blues don't hit anything like heroin, dilauded, oxy, or any other naturally derived opioid; the long heavy, almost psychadelic, experience is completely absent, but rather in it's place it has a rush that's like, 10x it's strength (at bioequivalent doses), so be prepared for the freight train, or i guess the bus in this case.
• lastly, blues (and a majority of benzofuranes, as well as fentanyl too) have a very very short half life, whereas tar for example will give you a good 3-5 hours of fucked-up-ness (depending on tolerance), a first time user of blues and/or fentanyl with no tolerances can see the effects lasting just about an hour.
• it's highly recomended to take a polydrug combo to increase lethality, namely [opioid+benzo/barbituate] or [opioid+benzo/barbituate+opioid potentiator] (ive listed a few of below with my preferences), but please note that you should be prepared to stagger your drugs according to their individual onset of effect/peak blood plasma content times, as every one will be different depending on drug AND ROA:
  • benzos (xanax, valium, ativan, temazepam, oxazepam, flubromazepam (of the benzos, this one is prefered), etc.)
  • barbituate
    • methylphenobarbidal (prefered, over any benzo or barbituate) is commonly sold as "xanax" by the same people selling blues
    • phenobarbidal (i think this site calls it "N"?)
    • quaaludes (if you somehow find them, defs worth just to try, but pretty sure they're gone forever lol)
  • amyltryptaline (potentiator)
  • dextromethorphan, nighttime only (potentiator)
  • benedryl (nod-enhancer, helps with nausea)
  • (some sources (bluelight forums users) say clonidine can potentiate opioid effects, though i have not researched this)

last, and most importantly, you NEED to make sure that nobody will find you for bare minimum of an hour, preferably 2 or more, after you do whatever you decide.
MANY PEOPLE CARRY NARCAN, and can reverse an opioid overdose.
similarly, EVERY ambulance and hospital has drugs that can reverse benzo toxicity.
even if your heart and respiration had fully stopped, theres a chance you can be rescuscitated if you're found to soon (learned this the hard way lol)

I thibk this is the UK version of what you are referring to...

BBC News - Nitazenes: Warning over super-strength street drugs linked to deaths - BBC News

Nitazenes: Warning over super-strength street drugs linked to deaths

Charity says Scotland has been "slow to heed warnings” over the rise in nitazene painkillers.

www.bbc.co.uk

 

[thatisitguy]

heyyo, just an fyi, fentanyl has a really low oral bioavailability (probably even moreso if they're blues, bc those things are compressed so fucking tightly you could probs use em to break a windshied. tried crushing one on my phone screen the first time, totalled my phone and literally ripped a hole in my dollar bill. i even started using a hammer for a bit lmao)

your best bet for blues is to vaporize em off a foil, but they are INCREDIBLY poorly dispersed (i.e. vaporizing one half of a pill migh barely get you high, while a literal crumb from the same pill on the other side might be enough to overdose. i seen many a seasoned junkie fall victim to it, on the hotspot where i used to live, it was almost an every-other-day occurence it seems like

also, another thing to take into account is the possibility they might not be fent, but nitazenes instead (common in my [old] area, more specifically etidonozene). honestly the way benzofuranes have been being developed, it's really hard to get a guage on bioavailabilities, usually its pretty safe to assume vaporization will be consistently high though.

(i also have never met ANYONE that's tried shooting them, so idk if it'd actually even work, i do know they're extremely poorly water soluble though)

idk much about the first one, but if your only ROA is oral, i'd say it's not gonna work. even if you managed to black out without puking, you'll just throw it up in your sleep. "best" possible scenario is you choke on your vomit, which leads to you potentially waking up at least partially (due to adrenaline), and that's a fucking awful way to go.

oxy is more 50/50, depending on the preparation. if it's roxicodone brand, it is in fact possible to vaporize them, but all other brands (that i'm aware of) take in depth pharmicokinetic knowledge (far past me, at least) in order to not just cinder and denature. if you do a cold water extraction, you'd be able to remove the oxy from the acetaminophen, and then make a liquid solution from it which you could plug (wouldn't recomend shooting, pills have high probability of causing clots quickly, which might prevent the drug from actually reaching your (liver i think?)), or if you're willing to risk potential sepsis, IM injection would be possible, but if you don't succeed, shit might suck.

as for the heroin (my truest love; it's all blues and fetty round here), i am QUEEN of the intramuscular injection, it's always been my favorite ROA for heroin, just can't do it often, bc necrosis risk lol. but to answer you, it's almost identical in bioavailability to IV (assuming you get it into muscle, not fat or skin), like 98% im to 99% iv, the come up time is about like 3 or 4 times as long as iv i wanna say? it's honestly still really quick, you just don't really get that overwhelming rush that you do from iv, it feels a lot more like the smoking high, maybe a lil more intense tho.

finally, nitazenes (if you google "benzofuranes" you can find most types on wikipedia, though bluelight has tons of firsthand if you're willing to dig)
there is SUCH a broad variety (increasing all the time) to these that there's no one rule to tell you absolutely how strong they'll be, HOWEVER if you exclude most of the iso- and like 75% of the proto- family of nitazenes, they're usually anywhere from 100x-10,000x the potentcy of fentanyl per gram, however, the manufacturers do (usually) put in the absolute bare minimum effort to make them *feel* as strong as whatever it's being sold as. if you can get your hands on etidonozene in bulk, itll be lights ouf from the second it even touches your mucas membranes/blood. there's a story of the inventor, a guy from slc, who upon synthesis started using, and by the time he was caught and forced to quit, they put him on like 10 times the max dose of [subs?/methadone? which ever one has agonist/partial antagonist combo], his withdrawals were still so insanely intense he ctb by his own hand (if that says anything about its potency?).
also, yeah they'll definitely make you nauseous, but usually you don't even notice because it's lights out the second you come up, unless you have a micrometer calibrated scale somehow? (also this is assuming they're pure)
it's also possible (and pretty quick) to develop a slight synthetic opioid tolerance which basically curbs the nausea (note: idk why, but in my experience fent and benzofurane nausea act similarly enogugh, a weirdly if you switch from fent to tar/oxy/hydro/etc or benzofuranes to tar/oxy/hydro/etc the nausea is like the first time all over again

That's what I am talking about. I see these PSAs about one grain of fentanyl can kill you yet clearly that is the 1 in a million odd. I also used test strips on a random sample of my stash and it all tested positive for fentanyl. I don't know if it was laced with other stuff, but what I had was fentanyl.

I could score some heroin. I just thought fentanyl was way more dangerous. It's amazing how hard it is to kill your body.

Can you shoot up fentanyl intramuscularly?

so while you are correct that an increased volume would increase the rate of absorption, the increase is non-linear
(i think the word i'm looking for is a "logarithmic scale"? i.e it increases very gradually up to a point in which it spikes rapidly (but doing so would require having surface volume begin to catch up to or be greater than total volume of contents, it is genuinely not humanly possible to achieve)
the reason that i argue to substitute your ROA, isn't necessarily for increased bioavailability, but rather because (even with an anti-emetic, or 100) at doses required for lethality, the opioid nausea is not only triggered by muscinic receptors (i.e. hystamines, etc.; the transporter 99% of anti-emitics work on), but also seratogenic, dopaminic, anf neuroepinephrin receptors, essentially triggering your body to realize "hey, there's something in me that's fucking shit up, time to puke, and puke, and once there's nothing left, puke some more!"
therefore if all of the drug is in your stomach, an overwhelming majority is never going to even get the chance to be absorbed, no matter what type of cyp450 matabolic wombo combo you've got genetically encoded in your gut.
if there's an option to either put it in your butt (or biochemical extractio devised to make it IV or IM possible), just so once that purge response is inevitably triggered, your body won't be able to get it out.

as for the oxys (actual oxy) the same rules apply (except with the added possibility of vaporization if its exclusively the roxicodone brand)

ahhh okay, i know exactly what you're talking about, in my area we call them "blues", though I've also heard the term "dirty-30" thrown around lol.
so there's a couple things that you should keep in mind with these (assuming they're similar to the ones out here, which, honestly, very likely are if you're in the usa, canada, or central america):

• first (least importantly), be warned that these things will OBLITERATE anything glass if you try to crush them on it (also, will tear through dollar bills, plastic baggies, any paint, soft woods, etc. i've always had the best luck putting them on something sturdy, and just going buckwild with a hammer/back of a screwdriver/etc (make sure to like, tripple baggie them first, pieces will go everywhere otherwise).
• second, i have no idea what else goes in these things, but they seem to be both water and lipid inspluble, even when applied to heat, vigorous agitation, or strong household acids or base reactions (pure ascetic acid, calcium carbonate); meaning that they're essentially impossible to shoot (both iv and im), with extremely diminished results (i have yet to personally test, so this is secondhand info) in oral roa as well. earlier today i read a thread where someone took 30 orally and had no result (but, once again, i am entirely unsure how truthful this is considering this is the internet), however based my own research, this seems plausible. insufflation works, but it seems to be noticably weaker (than vaporization), by my best guesses, at least <1/2. i would assume since they are both mucus membranes, rectal ROA could potentially work (and if so, would be considerably higher bioavailability than snorting). ALL OF THAT BEING SAID: everyone i've ever met that uses blues vaporized it (if you know how to roll it along foil without burning it already no need to read my cheats ahead lol)
• the easiest way i've found (as a beginner, that is, because rolling is definitely no easy feat) is to first, crush all of your product, as finely as you humanly can, then take a rectangle of tinfoil (idk maybe like 8×4ish?) and fold it in half until it becomes a square. make sure you've folded it as tightly as you can, if the layerd are too far apart, it wont heat up enough. then, make a small, wide groove in the foil (like, 1/2 finger depth maybe, 2 fingers wide, 1 finger long?), this will be your pocket to ensure nothing falls out. as evenly and thinly as you can, spread your product over and around the groove. then, with your straw in your mouth (it's especially helpful if it has a trumpet shape on the far end), keeping the foil side of the straw no closer than 1" away from the foil, use a lighter to heat the foil from underneath. play with distances, you'll definitely notice when it starts vaporizing (and it also has the thickest, most vile chemical smell you've probably ever smelled; it will stick to a room for at least a day lol).
• to get the most out of a HIGH: start from the extremeties of the foil, even if there's no product there, and slowly move around and inward (inhaling the vapor as you go)
• to get the most product in your system before passing out CTB METHOD: use your lighter to heat up as much of the product as possible without it vaporizing (i.e like 2-3x distance as vaporizing, the goal isn't to get the foil warm (itll lose heat immediately) but to kinda prebake your product so it requires less effort to go). once youve done your best there, start dead center, but make sure you don't overinhale and fill your lungs with toomuch air, every millisecond counts here. move your lighter in an outward spiral, following the direction with your straw. chances are that you won't make it all the way through your product (but if you've put enough on, it won't matter) (hell, if you hit a hotspot (something blues are notorious for) you might not even need 1/10th of a pill)
• be warned, it's 0-60 in like 2 seconds flat, and if you're not familiar with the sensation, it can be pretty overwhelming (but still kinda enjoyable)
• side note: blues don't hit anything like heroin, dilauded, oxy, or any other naturally derived opioid; the long heavy, almost psychadelic, experience is completely absent, but rather in it's place it has a rush that's like, 10x it's strength (at bioequivalent doses), so be prepared for the freight train, or i guess the bus in this case.
• lastly, blues (and a majority of benzofuranes, as well as fentanyl too) have a very very short half life, whereas tar for example will give you a good 3-5 hours of fucked-up-ness (depending on tolerance), a first time user of blues and/or fentanyl with no tolerances can see the effects lasting just about an hour.
• it's highly recomended to take a polydrug combo to increase lethality, namely [opioid+benzo/barbituate] or [opioid+benzo/barbituate+opioid potentiator] (ive listed a few of below with my preferences), but please note that you should be prepared to stagger your drugs according to their individual onset of effect/peak blood plasma content times, as every one will be different depending on drug AND ROA:
  • benzos (xanax, valium, ativan, temazepam, oxazepam, flubromazepam (of the benzos, this one is prefered), etc.)
  • barbituate
    • methylphenobarbidal (prefered, over any benzo or barbituate) is commonly sold as "xanax" by the same people selling blues
    • phenobarbidal (i think this site calls it "N"?)
    • quaaludes (if you somehow find them, defs worth just to try, but pretty sure they're gone forever lol)
  • amyltryptaline (potentiator)
  • dextromethorphan, nighttime only (potentiator)
  • benedryl (nod-enhancer, helps with nausea)
  • (some sources (bluelight forums users) say clonidine can potentiate opioid effects, though i have not researched this)

last, and most importantly, you NEED to make sure that nobody will find you for bare minimum of an hour, preferably 2 or more, after you do whatever you decide.
MANY PEOPLE CARRY NARCAN, and can reverse an opioid overdose.
similarly, EVERY ambulance and hospital has drugs that can reverse benzo toxicity.
even if your heart and respiration had fully stopped, theres a chance you can be rescuscitated if you're found to soon (learned this the hard way lol)

So basically you're saying that I should smoke the pills, not swallow? To be clear, I am not looking to get high; I'm looking to CTB.

 

[fallingasl33p]

Another good option for opiates I'd considered for a long time is methadone. I remember being told just the daily dose they hand out to those with addiction issues would be enough to take out someone who's totally opioid-naive. There's case studies/examples out there if you want to explore for yourself. It's just the obtaining it that's the issue obviously and that's what usually always ends up being my biggest obstacle.

 

[Richard Langford]

Another good option for opiates I'd considered for a long time is methadone. I remember being told just the daily dose they hand out to those with addiction issues would be enough to take out someone who's totally opioid-naive. There's case studies/examples out there if you want to explore for yourself. It's just the obtaining it that's the issue obviously and that's what usually always ends up being my biggest obstacle.

As in pills?
You know about this (see below) ?

Thread 'Protonitazene masquerading as Oxycontin' https://sanctioned-suicide.net/threads/protonitazene-masquerading-as-oxycontin.195338/

 

[fallingasl33p]

Nah the solution. Physeptone. Much more commonly used than tablets.

And I've read plenty about accidental nitazene related OD when just taken orally. Anything with needles I'm very wary of especially IM not IV. But anything like IV injection or snorting where there's going to be very rapid absorption into the bloodstream my fear would be you don't get enough ingested to be fatal before going unconscious or something. But also isn't there the issue that some pills aren't even properly absorbed by the nasal/oral mucosa? Rectal administration eliminates the need for anti-emetics but those aren't a problem for me personally. But again very rapid absorption. I'm by no means an expert if that's not obvious. I just know which method of administration I'm favouring personally if I can make sure nausea/vomiting won't be an issue.

 

[Richard Langford]

Nah the solution. Physeptone. Much more commonly used than tablets.

And I've read plenty about accidental nitazene related OD when just taken orally. Anything with needles I'm very wary of especially IM not IV. But anything like IV injection or snorting where there's going to be very rapid absorption into the bloodstream my fear would be you don't get enough ingested to be fatal before going unconscious or something. But also isn't there the issue that some pills aren't even properly absorbed by the nasal/oral mucosa? Rectal administration eliminates the need for anti-emetics but those aren't a problem for me personally. But again very rapid absorption. I'm by no means an expert if that's not obvious. I just know which method of administration I'm favouring personally if I can make sure nausea/vomiting won't be an issue.

I've read plenty too about accidental ODs.

The concern re just crushing them and taking them with water is bringing them back up.

Your concern re IM is infections and the like?

I'd rather not snort as I'm concerned about not getting enough in me (as you say) before passing out.

 

[fallingasl33p]

I've read plenty too about accidental ODs.

The concern re just crushing them and taking them with water is bringing them back up.

Your concern re IM is infections and the like?

I'd rather not snort as I'm concerned about not getting enough in me (as you say) before passing out.

Obviously there's risk of infection or other complications if you hit the wrong spot (which I guess aren't exactly a concern if you're already catching the bus) but I just heard that absorption can much more unreliable. Again I don't claim to be an expert but it was just something I read about when exploring self admin methods personally.

 

[Richard Langford]

Obviously there's risk of infection or other complications if you hit the wrong spot (which I guess aren't exactly a concern if you're already catching the bus) but I just heard that absorption can much more unreliable. Again I don't claim to be an expert but it was just something I read about when exploring self admin methods personally.

Its supposed to be 97% bioavailability.

 

[fallingasl33p]

And re crushing and drinking I would just say a strong anti-emetic + a know some methods suggest some kind of stomach acid inhibitor but I've read mixed opinions on the latter part of the equation. I think a MAID instructional I read had said x3 metclop 10mg and x2 ondansetron

 

[Richard Langford]

And re crushing and drinking I would just say a strong anti-emetic + a know some methods suggest some kind of stomach acid inhibitor but I've read mixed opinions on the latter part of the equation. I think a MAID instructional I read had said x3 metclop 10mg and x2 ondansetron

For opioid nausea specifically?

 

[fallingasl33p]

It's supposed to be 97% bioavailability.

Well maybe I got bad intel. For the amount of research/forums/PPH versions I've read and rabbit holes I've gone down over the years when I get set on a certain method in my mind I couldn't point you to a single reliable source on that one I'm afraid.

 

[Richard Langford]

Well maybe I got bad intel. For the amount of research/forums/PPH versions I've read and rabbit holes I've gone down over the years when I get set on a certain method in my mind I couldn't point you to a single reliable source on that one I'm afraid.

It IS extremely difficult to get inforned info on this site. SN yes but things like Opioids not unfortunately.

 

[fallingasl33p]

For opioid nausea specifically?

Not specifically but including. Just look at existing MAID protocols for an idea of the quantity of opioids being given

 

[Richard Langford]

Not specifically but including. Just look at existing MAID protocols for an idea of the quantity of opioids being given

Those are typically vast doses. 15 grms of Amitriptyline for example.

 

[fallingasl33p]

Those are typically vast doses. 15 grms of Amitriptyline for example.

Oh yes I'm aware a layman attempting the actual protocol themselves wouldn't be feasible but I'm just saying the antiemetics used are sufficient for the 3-15g of morphine used in those cases lol
I think you'd struggle to get your hands on much more than what I've mentioned in the way of anti-emesis…?

 

[Richard Langford]

Oh yes I'm aware a layman attempting the actual protocol themselves wouldn't be feasible but I'm just saying the antiemetics used arei presume sufficient for the 3-15g of morphine used in those cases lol
I think you'd struggle to get your hands on much more than what I've mentioned in the way of anti-emesis…?

Ok, I see you point. Unfortunately, while I can get oral Morphine I cant get injectible. I presume they're talking that .

 

[fallingasl33p]

No actually the MAID protocols are think are mostly all oral administration since it's the act of swallowing it yourself that's in keeping with the law. It's just that fact they're able to extract the doses required of each drug from all the other excipients that's the biggest hurdle for the rest of us.
But anyway that's besides the point since you're not planning on involving any of the other drugs in the protocol that's a whole other topic.

 

[Richard Langford]

No actually the MAID protocols are think are mostly all oral administration since it's the act of swallowing it yourself that's in keeping with the law. It's just that fact they're able to extract the doses required of each drug from all the other excipients that's the biggest hurdle for the rest of us.
But anyway that's besides the point since you're not planning on involving any of the other drugs in the protocol that's a whole other topic.

I don't think realistically theres any way a person could orally take in 3-15mg of morphine and not experience nausea. Arguably, maybe if you had an extremely high tolerance but most of us don't.

No, im looking on these pills online masquerading as Oxycontin.

 

[fallingasl33p]

I don't think realistically theres any way a person could orally take in 3-15mg of morphine and not experience nausea. Arguably, maybe if you had an extremely high tolerance but most of us don't.

No, im looking on these pills online masquerading as Oxycontin.

That's what the metoclopramide and ondandestron 30 minutes prior is for brother

 

[Richard Langford]

That's what the metoclopramide and ondandestron 30 minutes prior is for brother

Doubt that would help for such vast amounts unless you had a pretty big tolerance.