I too had a very bad experience with Quetiapine. Quetiapine is a second generation antipsychotic my shrink prescribed for me because the first generation antipsychotic that worked for 26 years, was not available for a while in the US. Didn't occur to me to look online for that first gen. med through Canadian Pharma websites. I got good, sound sleep while on Quetiapine, however, from the first day I was on it, I had acute urinary retention to such I could not urinate at all, (googling it now I see urinary retention is a possible side effect to Quetiapine) plus I was in a state of panic from the time I got up until the time I went to bed. Lost 15 pounds in only two weeks due to not being able to do more than choke down yogurt and toast. This drug is not FDA approved for either anxiety or sleep. Like the poster Futility wrote, don't want to scare anyone but the negatives need to be shared too. I didn't have a good reaction to another second generation med, Risperidone, either. Thankfully I got a good supply of the first generation med out of Canada, and also now it is available again in the US.